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Glycosylated haemoglobin (HbA 1c ) in iron‐ and vitamin B12 deficiency
Author(s) -
GRAMHANSEN P.,
ERIKSEN J.,
MOURITSANDERSEN T.,
OLESEN L.
Publication year - 1990
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1990.tb00131.x
Subject(s) - vitamin b12 , glycosylated haemoglobin , medicine , iron deficiency , endocrinology , hemoglobin , population , anemia , diabetes mellitus , type 2 diabetes , environmental health
Abstract. Glycosylated haemoglobin (HbA 1c ) was measured in 10 patients with iron deficiency anaemia, 10 patients with vitamin B12 deficiency anaemia and 10 healthy controls. Initially there were no significant differences between the groups ( P > 0.4), but after treatment with iron and vitamin B12 for 3 and 6 weeks, the glycosylated haemoglobin concentration decreased significantly ( P < 0.01). It was concluded that glycosylated haemoglobin is a sensitive marker of the changes in the erythrocyte population that are observed when predominantly immature erythrocytes are being produced.