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Hyposelenaemia: patients with gastrointestinal diseases are at risk
Author(s) -
BJERRE B.,
SCHENCK H.,
SÖRBO B.
Publication year - 1989
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1989.tb00044.x
Subject(s) - selenium , medicine , gastroenterology , gastrointestinal disease , selenium deficiency , gastrointestinal tract , retrospective cohort study , gastrointestinal cancer , serum concentration , disease , cancer , glutathione peroxidase , metallurgy , materials science , catalase , oxidative stress , colorectal cancer
. A retrospective study of serum selenium determinations performed in a hospital laboratory revealed 47 cases of hyposelenaemia (defined as a serum selenium level below 0.74 μmol l −1 ). Moderate hyposelenaemia (serum selenium 0.30–0.55 μmol l −1 ) was found in 11 patients and seven of these suffered from gastrointestinal diseases. Furthermore severe hyposelenaemia (serum selenium below 0.30 μmol l −1 ) was detected in three patients, who were all affected by gastrointestinal disease. We concluded that patients with gastrointestinal diseases are especially at risk of developing selenium deficiency and should be monitored by repeated determinations of serum selenium. Patients with moderate or severe hyposelenaemia should receive selenium treatment.