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THE EFFECTS OF UNSATURATED AND SATURATED DIETARY FATS ON PLASMA CHOLESTEROL, PHOSPHOLIPIDS AND LECITHIN: CHOLESTEROL ACYLTRANSFERASE ACTIVITY
Author(s) -
Gjone Egil,
Nordøy Arne,
Blomhoff Jan Petter,
Wiencke Ingrid
Publication year - 1972
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1972.tb00088.x
Subject(s) - lecithin , cholesterol , sterol o acyltransferase , lecithin—cholesterol acyltransferase , medicine , endocrinology , soybean oil , acyltransferase , food science , unsaturated fat , chemistry , saturated fat , biochemistry , enzyme , lipoprotein
The plasma concentrations of cholesterol, individual phospholipids and the activity of plasma lecithin: cholesterol acyltransferase (LCAT) have been examined in two groups of healthy subjects on different diets. The diets were isocaloric with 40% fat. One group received a diet rich in unsaturated fatty acids, in which soybean oil was the fat source. The other group was given a saturated fatty acid diet with medium chain triglycerides (MCT). A significant fall in the plasma concentrations of cholesterol and lecithin was observed after 21 days' use of the soybean oil diet. Concomitantly a significant reduction in the plasma LCAT activity also took place. In the control group on MCT diet no significant changes in plasma lipid concentrations or LCAT activity were noted. The influence of dietary changes on plasma LCAT activity is discussed.