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PENTAGASTRIN‐ AND INSULIN‐INDUCED SECRETION IN DIABETES MELLITUS
Author(s) -
Langer L.
Publication year - 1972
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1972.tb00086.x
Subject(s) - pentagastrin , medicine , diabetes mellitus , gastric emptying , insulin , endocrinology , stomach , gastric acid
The insulin test has been accepted as the most reliable means of evaluating vagal function. A modified form of it—combined insulin/pentagastrin test—demonstrated in a controlled study that the vagal influence on gastric secretion is reduced, suggesting vagal dysfunction in 10 diabetics with an average duration of diabetes of 15 years without symptoms from the gastro‐intestinal tract. This agrees with the contention that delayed gastric emptying is another sign of vagal dysfunction.

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