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THE HAEMODYNAMIC EFFECT OF INTRAVENOUS INJECTION OF LEVODOPA
Author(s) -
Moorthy Sreenivasa,
Grendahl Helge,
Andersen Anders,
Müller Carsten
Publication year - 1972
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1972.tb00083.x
Subject(s) - medicine , cardiac output , nausea , stroke volume , vascular resistance , anesthesia , cardiology , heart rate , cardiac catheterization , peripheral , hemodynamics , levodopa , tachycardia , pulmonary artery , stroke (engine) , peripheral resistance , blood pressure , disease , parkinson's disease , mechanical engineering , engineering
Levodopa has been given in a dose of 100 to 200 mg into the pulmonary artery of eight patients with heart disease undergoing routine catheterization studies. The cardiac rate, the systemic and pulmonary arterial pressures, the cardiac output, the stroke volume and peripheral resistance were calculated. Tachycardia was found in all patients. Ventricular premature contractions were seen in two patients. An initial fall followed by a rise in systemic arterial pressures; rise in cardiac output, rise in stroke volume, and fall in peripheral resistance were observed in the majority of patients. Nausea was the commonest side‐effect.