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FATTY ACID COMPOSITION OF ADIPOSE TISSUE IN MALE NORWEGIANS WITH MYOCARDIAL INFARCTION
Author(s) -
Kirkeby Knut,
NitterHauge Sigurd,
Bjerkedal Inger
Publication year - 1972
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1972.tb00058.x
Subject(s) - medicine , adipose tissue , myocardial infarction , linoleic acid , polyunsaturated fatty acid , obesity , population , incidence (geometry) , infarction , coronary heart disease , fatty acid , physiology , endocrinology , cardiology , biochemistry , biology , environmental health , physics , optics
Gas‐chromatographic studies of the fatty acid composition of adipose tissue specimens have been carried our in 70 urban men with acute myocardial infarction (AMI) and in a control group comprising 25 healthy men of comparable age. Only subjects living free of dietary instructions were included in the study. Samples of adipose tissue obtained from patients with infarction who had had known coronary heart disease (CHD) for at least one year contained significantly higher mean linoleic acid than samples from patients with no history of previous heart disease or from healthy subjects. The difference between mean linoleic acid content in the two latter groups was also statistically significant, with the lowest values found in patients with infarction but without known previous CHD. Diet is assumed to be the dominant factor responsible for the discrepancy in fatty acid composition. Patients with known CHD have probably been more assiduous in following recent widespread nutrional advice recommending increased intake of polyunsaturated fats than the population as a whole. Male Norwegians living in urban areas exhibited almost the same adipose tissue fatty acid patterns as the inhabitants of countries with high incidence of CHD.