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A POPULATION STUDY ON MONOCLONAL GAMMAPATHY
Author(s) -
Axelsson U.,
Hällén J.
Publication year - 1972
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1972.tb00020.x
Subject(s) - medicine , population , surgery , environmental health
Serum electrophoresis included in a medical survey in 1964 of 6 995 subjects above 25 years of age revealed M‐components in 64. One had myelomatosis. Five and a half years later 16 persons had died and 9 had moved or refused to take part in this study. The concentrations of the M‐components in the remaining 39 cases were essentially unchanged. This finding suggests a benign, monoclonal gammapathy. The series represented an observation time of 247 patient‐years, during which malignant gammapathy had not developed. Among the 6 931 subjects without serum M‐components two had been hospitalized for myelomatosis during the 6 years after the mass examination. In one of these there was only a urinary discrete component and in the other the diagnosis was not well‐founded.