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Endometrial adenocarcinoma presenting in a premenopausal patient with tuberous sclerosis
Author(s) -
Jaffe J. S.,
Chambers J. T.
Publication year - 2005
Publication title -
journal of intellectual disability research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 104
eISSN - 1365-2788
pISSN - 0964-2633
DOI - 10.1111/j.1365-2788.2005.00685.x
Subject(s) - tuberous sclerosis , medicine , adenocarcinoma , gynecology , endometrial cancer , pediatrics , cancer , psychiatry
Background Endometrial adenocarcinoma is very uncommon in women under 40 years of age. Case A 39‐year‐old woman with tuberous sclerosis and severe intellectual disability presented with irregular bleeding unresponsive to oral contraceptive therapy. She was subsequently found to have a deeply invasive endometrial adenocarcinoma. Conclusion Caregivers must pay particular attention to signs and symptoms in non‐verbal patients. Persistent irregular bleeding on oral contraceptive therapy warrants additional evaluation.