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Mathematical skills in Prader–Willi Syndrome
Author(s) -
Bertella L.,
Girelli L.,
Grugni G.,
Marchi S.,
Molinari E.,
Semenza C.
Publication year - 2005
Publication title -
journal of intellectual disability research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 104
eISSN - 1365-2788
pISSN - 0964-2633
DOI - 10.1111/j.1365-2788.2004.00634.x
Subject(s) - wechsler adult intelligence scale , cognition , cognitive psychology , psychology , cognitive skill , mathematical problem , intelligence quotient , developmental psychology , neuroscience , mathematics education
Abstract Objectives  This paper investigates mathematical skills in Prader–Willi Syndrome (PWS), a pathological condition because of congenital alterations of chromosome pair 15. The following questions were addressed: (1) Are mathematical skills in PWS relatively more impaired with respect to other cognitive functions (as has been repeatedly but anecdotally reported)?; and (2) What is the nature of the mathematical impairment? Methods  The first study employed the Wechsler Adult Intelligence Scale (WAIS) and an extensive battery of cognitive tasks for which norms are known. Both batteries include a mathematical section. The second study used a theoretically motivated series of mathematical tasks specifically designed to individually assess the different cognitive components underlying mathematical skills. Results  Mathematical skills were found to be the most impaired cognitive abilities together with short‐term memory capacity. No specific mathematical domain was seen to be unaffected in PWS participants. The clearest deficits observed concern ‘syntactic’ processes in number transcoding, multiplication, number facts retrieval and calculation procedures. Conclusion  Failure of mathematical skills is the most distinctive feature in the cognitive profile of PWS. However, to determine whether this is indeed a specific pattern of performance related to PWS, results must be compared with those obtained with patients manifesting other genetic disorders.

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