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Divalproex‐responsive rapid cycling bipolar disorder in a patient with Down's syndrome: implications for the Down's syndrome‐mania hypothesis
Author(s) -
SOVNER R.
Publication year - 1991
Publication title -
journal of intellectual disability research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 104
eISSN - 1365-2788
pISSN - 0964-2633
DOI - 10.1111/j.1365-2788.1991.tb01048.x
Subject(s) - mania , rapid cycling , valproic acid , bipolar disorder , divalproex , psychology , psychiatry , down syndrome , mood stabilizer , pediatrics , medicine , lithium (medication) , epilepsy
. A case of rapid cycling bipolar disorder in a person with Down's syndrome, responsive to divalproex sodium, a valproic acid derivative, is presented. This case and three other reported cases of mania in association with Down's syndrome suggest that this chromosomal disorder does not preclude the development of mania.