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Increased activity of pyridoxal kinase in tongue in Down's syndrome
Author(s) -
COBURN S. P.,
MAHUREN J. D.,
SCHALTENBRAND W. E.
Publication year - 1991
Publication title -
journal of intellectual disability research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 104
eISSN - 1365-2788
pISSN - 0964-2633
DOI - 10.1111/j.1365-2788.1991.tb00452.x
Subject(s) - pyridoxal , pyridoxamine , phosphatase , pyridoxal 5 phosphate , medicine , endocrinology , kinase , chemistry , pyridoxal phosphate , enzyme , biochemistry , cofactor
. The concentrations of B 6 vitamins, and the activities of pyridoxal kinase, pyridoxamine phosphate oxidase and pyridoxal phosphate phosphatase were measured in tongue. Pyridoxal kinase activity was significantly greater ( P <0.01) in Down's syndrome subjects compared with controls.