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The Fragile‐X syndrome in twin sisters
Author(s) -
COWIE V. A.,
SINGH K. RAMESHWARI,
WHEATER R.,
BIRD J.
Publication year - 1987
Publication title -
journal of intellectual disability research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 104
eISSN - 1365-2788
pISSN - 0964-2633
DOI - 10.1111/j.1365-2788.1987.tb01344.x
Subject(s) - psychosis , psychology , fragile x , cognition , obligate , fragile x syndrome , lesion , developmental psychology , psychiatry , genetics , biology , ecology , gene
. Two mentally handicapped dizygotic twin sisters were found to possess the Fragile‐X lesion. They showed different levels of cognitive deficit. The hypothesis that the level of cognitive function in female carriers of the Fragile‐X lesion may be influenced by Lyonization is discussed. The mother of the twins was schizophrenic. Although she was an obligate carrier her psychosis was thought not to be causally connected with the Fragile‐X status.