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XYLOSE ABSORPTION IN DOWN'S SYNDROME
Author(s) -
Williams Celia A.,
Quinn Helen,
WRIGHT Elaine C.,
Sylvester P.E.,
Gosling Paula J.H.,
Dickerson J.W.T.
Publication year - 1985
Publication title -
journal of intellectual disability research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 104
eISSN - 1365-2788
pISSN - 0964-2633
DOI - 10.1111/j.1365-2788.1985.tb00325.x
Subject(s) - wright , art history , art
A standard xylose absorption test was carried out in 14 people with Down's syndrome (DS) and in 14 age-matched mentally deficient controls; a further 30 people with DS were similarly investigated. Mentally deficient people as a group were found to have impaired xylose absorption, the matched DS subjects having a significantly reduced xylose absorption (P less than 0.001) when compared to the mentally deficient controls. Ninety percent of the DS subjects had a xylose excretion below the normal range. At present it is not possible to identify the cause of the malabsorption but it is highly likely that the malabsorption plays a role in a number of the vitamin and mineral deficiencies found in people with DS.