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PRE‐ATHEROSCLEROTIC LESIONS IN DOWN SYNDROME
Author(s) -
MOSS T. J.,
AUSTIN G. E.
Publication year - 1980
Publication title -
journal of intellectual disability research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 104
eISSN - 1365-2788
pISSN - 0964-2633
DOI - 10.1111/j.1365-2788.1980.tb00067.x
Subject(s) - reprint , citation , medicine , library science , gerontology , psychology , computer science , physics , astronomy
Autopsy examination of seven non-institutionalised Down syndrome patients (age ten to twenty-five years) revealed normal prevalence of pre-atherosclerotic lesions. Atherosclerotic plaques were observed in one of these subjects (age fourteen years), refuting reported implications that this population is atheroma-free. However, atheromatous aortic lesions were not seen in an eighth subject (age fifty years), raising the possibility that an atheroma-free subgroup of patients with Down syndrome may exist.