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SOME ASPECTS OF CARBOHYDRATE METABOLISM IN PRADER‐WILLI SYNDROME
Author(s) -
SAREEN CHANDRA,
RUVALGABA R. H. A.,
KELLEY V. C.
Publication year - 1975
Publication title -
journal of intellectual disability research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 104
eISSN - 1365-2788
pISSN - 0964-2633
DOI - 10.1111/j.1365-2788.1975.tb01264.x
Subject(s) - medicine , library science , gerontology , pediatric endocrinology , pediatrics , computer science
Three patients with Prader-Willi syndrome are reported. The subjects presented chemical diabetes mellitus. All patients were hypersentsiive to exogenous insulin and they showed poor adrenal medullary response to hypoglycaemics. It was postulated that the poor adrenal medullary response to the insulin injection may be a contributing factor in the excessive hypoglycaemic response, and that the diabetes mellitus observed in the patients could be due to inactivation of endogenous insulin.