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Reduction in sodium chloride intake: effects on urinary Na, K and aldosterone output in healthy free‐living adults
Author(s) -
Mathers J. C.
Publication year - 1988
Publication title -
journal of human nutrition and dietetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.951
H-Index - 70
eISSN - 1365-277X
pISSN - 0952-3871
DOI - 10.1111/j.1365-277x.1988.tb00184.x
Subject(s) - medicine , aldosterone , sodium , zoology , urine , urinary system , excretion , endocrinology , biology , chemistry , organic chemistry
Eleven healthy free‐living adults (six women, five men) weighed and recorded all food and drink consumed and collected all urine for two non‐consecutive 7‐day periods whilst eating their usual diet (Period 1) and attempting to reduce salt intake (Period 2). Bread (including pitta bread) provided on average a quarter of total Na intake of subjects in Period 1 so that wholemeal bread made without added salt was made available in Period 2. All subjects achieved substantial reductions (mean 65%) in Na intake in Period 2 with no change in K intake so that the Na:K molar ratio fell from 1.3 to 0.5. Urinary Na output closely followed intakes and there was a large increase (mean 11.2 μg/d) in aldosterone excretion with a non‐significant increase in K output. Simple linear relationships which allow prediction of Na and K intake from the more easily measured urinary output were derived.