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Do extracellular products of Aeromonas salmonicida induce thrombosis by entering the fish coagulation system at factor X?
Author(s) -
SALTE R.,
NORBERG K.,
ØDEGAARD O. R.
Publication year - 1991
Publication title -
journal of fish diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 85
eISSN - 1365-2761
pISSN - 0140-7775
DOI - 10.1111/j.1365-2761.1991.tb00839.x
Subject(s) - aeromonas salmonicida , coagulation , biology , coagulation system , extracellular , thrombus , fish <actinopterygii> , tissue factor , protease , aeromonas hydrophila , microbiology and biotechnology , thrombosis , von willebrand factor , immunology , fishery , biochemistry , medicine , platelet , enzyme
. Thrombosis of minute vessels is a common feature of acute furunculosis in Atlantic salmon. Crude extracellular products (F.CP) of Aeromans, salmonicida injected into the dorsal aorta of cannulated fish elicited an activation of the coagulations systems of the fish When screened with a number of chromogenic substrates, the ECP protease revealed a factor‐X like activity. Thus, it may he hypothesized that the ECP induces thrombosis by entering the fish coagulation systems at factor X. and that thrombus formation is a way of creating a site of infection.