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The effects of malachite green upon proliferative kidney disease
Author(s) -
CLIFTONHADLEY R. S.,
ALDERMAN D. J.
Publication year - 1987
Publication title -
journal of fish diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 85
eISSN - 1365-2761
pISSN - 0140-7775
DOI - 10.1111/j.1365-2761.1987.tb00725.x
Subject(s) - malachite green , malachite , biology , toxicity , rainbow trout , kidney , kidney disease , fish <actinopterygii> , medicine , physiology , endocrinology , chemistry , fishery , organic chemistry , adsorption , copper
. When rainbow trout infected with proliferative kidney disease (PKD) held in the laboratory were treated with malachite green and formalin to cure ichthyophthiriasis it was observed that subsequent development of PKD was delayed. Experiments are reported which indicate that this was due to the malachite green treatment. The possible use of malachite green in the treatment of PKD, tissue levels of malachite green achieved during treatments and the toxicity risks from multiple dose therapy with malachite green are discussed.