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The effects of the use of potassium alum adjuvant in vaccines against vibriosis in rainbow trout, Salmo gairdneri Richardson
Author(s) -
HORNE M. T.,
ROBERTS R. J.,
TATNER MARY,
WARD P.
Publication year - 1984
Publication title -
journal of fish diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 85
eISSN - 1365-2761
pISSN - 0140-7775
DOI - 10.1111/j.1365-2761.1984.tb00911.x
Subject(s) - rainbow trout , vibrio anguillarum , adjuvant , salmo , biology , alum , fishery , fish <actinopterygii> , veterinary medicine , vibrio , immunology , medicine , chemistry , bacteria , genetics , organic chemistry
. A formalized bacterin of Vibrio anguillarum , with and without alum adjuvant, was administered intraperitoneally to rainbow trout under farm conditions. Compared with the normal bacterin the adjuvanted preparation caused pathological changes indicative of chronic peritonitis, substantial early mortalities in 3 cm fish, and to a lesser extent in 20 cm fish, and depressed growth rate. No additional degree of protection against artificial challenge was obtained from its use.