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Asthma patients with low perceived burden of illness: a challenge for guideline adherence
Author(s) -
Schneider Antonius,
Biessecker Kathrin,
Quinzler Renate,
PharmD Petra KaufmannKolle,
Meyer Franz Joachim,
Wensing Michel,
Szecsenyi Joachim
Publication year - 2007
Publication title -
journal of evaluation in clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.737
H-Index - 73
eISSN - 1365-2753
pISSN - 1356-1294
DOI - 10.1111/j.1365-2753.2006.00756.x
Subject(s) - medicine , guideline , asthma , depression (economics) , quality of life (healthcare) , ambulatory , physical therapy , family medicine , nursing , pathology , macroeconomics , economics
Rationale and aims The reason why many patients seem to tolerate suffering from sub‐optimal treated asthma remains unclear. The aim was to evaluate the guideline adherence combined with quality of life of patients with moderate to severe asthma. Methods 256 asthma patients from 43 primary care practices in Saxony‐Anhalt filled in a questionnaire including the Asthma Quality of Life Questionnaire (AQLQ), the Patient Health Questionnaire (PHQ‐D) and questions evaluating the asthma severity, medication and self‐management. Results 43.4% suffered from moderate to severe asthma. Drug treatment accorded with guidelines in 36.9%, drug dosage of inhaled steroids was too low in 34.3%, and 21.5% were not treated according to guidelines. A total of 7.3% of the patients received end‐of‐dose therapy. AQLQ declined and depression rose with asthma severity and guideline non‐adherence ( P < 0.001). Only 29.1% received asthma education. However, 64.5% of the patients without education did not want to receive education. They had a higher quality of life, lower depression ( P < 0.001) and lower use of steroids ( P = 0.016). Higher depression scores where related with hospital admission (OR 3.29; 95% CI 1.57–6.87 for each quartile of PHQ‐D) and unscheduled home visits or ambulatory care (OR 1.58; 1.07–2.33). Conclusion There is a large variation of asthma severity which can partly be explained by the guideline adherence of medication and deficits of patients’ management. The perceived burden of illness plays a more important role for education and self‐management than the real severity of disease. Therefore, target‐oriented interventions are needed to identify and motivate patients at risk.