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Amisulpride augmentation after the failure of citalopram for depression: a case report
Author(s) -
Carvalho A. F.,
NunesNeto P. R.,
Cavalcante J. L.,
Oliveira Lima M. C.
Publication year - 2007
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/j.1365-2710.2007.00787.x
Subject(s) - amisulpride , citalopram , serotonergic , medicine , antidepressant , major depressive disorder , depression (economics) , dopaminergic , anesthesia , pharmacology , psychology , psychiatry , serotonin , schizophrenia (object oriented programming) , olanzapine , dopamine , anxiety , receptor , cognition , macroeconomics , economics
Summary This case report describes a 35‐year‐old woman with a first depressive episode. She was treated with the serotonergic antidepressant citalopram for 12 weeks without therapeutic response. Low‐dose amisulpride augmentation resulted in a significant clinical improvement. We hypothesize that the dopaminergic properties of amisulpride might augment the effects of serotonergic antidepressants in refractory patients.