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Opiate antagonists for the treatment of schizophrenia
Author(s) -
Welch E. B.,
Thompson D. F.
Publication year - 1994
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/j.1365-2710.1994.tb00814.x
Subject(s) - naltrexone , opiate , (+) naloxone , schizophrenia (object oriented programming) , narcotic antagonists , medicine , antipsychotic , psychiatry , psychology , pharmacology , antagonist , receptor
SUMMARY Numerous studies suggest that opiate antagonists may have antipsychotic properties. A review of the literature describing the use of naloxone to treat schizophrenic patients has shown mixed results. The three studies on naltrexone have found no benefit in controlling auditory hallucinations. We present a synopsis of these studies.