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Relationship between slime production, antibiotic sensitivity and the phagetype of coagulase–negative staphylococci
Author(s) -
Boussard P.,
Pithsy A.,
Devleeschouwer M. J.
Publication year - 1993
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/j.1365-2710.1993.tb00587.x
Subject(s) - microbiology and biotechnology , penicillin , antibiotics , coagulase , teicoplanin , erythromycin , biology , staphylococcus , vancomycin , bacteria , staphylococcus aureus , genetics
SUMMARY Three hundred and three strains of coagulase–negative staphylococci (CNS) were collected from the fingers of healthy donors (289) and from blood cultures (14). Twelve different species were identified (5 5. auricularis, 45 S. capitis, 15 S. cohnii, 86 S. epidermidis, 23 S. haemolyticus, 37 S. hominis, 1 S. lentus, 5 S. saprophyticus, 7 S. sciuri, 6 S. simulans, 54 5. xylosus and 19 5. warneri). Amongst these CNS strains, 151 were slime producers, 112 were phage–typable and 188, 133, 126 and 91 were, respectively, resistant to penicillin, teicopiamn, erythromicin and kanamycin. Slime–producing strains were resistant to at least seven antibiotics with a probability of 001 < P < 005. Non–slime–producing strains were sensitive to all the tested antibiotics with a probability of 0001 < P < 001. There was no direct relationship between antibiotic sensitivity and phage type, although a non–typable strain was more often resistant to seven or more antibiotics than a typable one (005 < P <01).