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PATTERNS OF OUT‐PATIENTS NON‐STEROIDAL ANTI‐INFLAMMATORY DRUG PRESCRIBING IN TWO TEACHING HOSPITAL RHEUMATOLOGY UNITS–IMPLICATIONS FOR POST‐MARKETING SURVEILLANCE
Author(s) -
Pullar T.,
Murphy B.,
Taggart A.,
Wright V.
Publication year - 1990
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/j.1365-2710.1990.tb00384.x
Subject(s) - nabumetone , diclofenac , medicine , naproxen , ibuprofen , medical prescription , rheumatology , flurbiprofen , postmarketing surveillance , over the counter , rheumatoid arthritis , pharmacoepidemiology , drug , family medicine , nonsteroidal , alternative medicine , pharmacology , adverse effect , pathology
Summary Patterns of prescriptions or recommendations for non‐steroidal antiinflammatory drugs (NSAIDs) were examined in the out‐patient departments of two teaching hospital rheumatology units [The General Infirmary, Leeds (w=140), and Musgrave Park Hospital, Belfast ( n = 77)]. In both units four drugs accounted for over 80% of prescriptions/recommendations (diclofenac, indomethacin, ibuprofen and naproxen in Leeds and flurbiprofen, nabumetone, ibuprofen and diclofenac in Belfast). In Leeds patients with pre‐existing upper gastrointestinal problems were more likely to receive diclofenac whereas in Belfast they were more likely to receive nabumetone or ibuprofen. In Leeds, patients who received indomethacin tended to be young males with seronegative arthritis. These differences between drugs and between centres could have important implications for cost, design and interpretation of studies of post‐marketing surveillance.