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ENDOTOXIN TESTING
Author(s) -
Vanhaecke E.,
Pijck J.,
Vuye A.
Publication year - 1987
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/j.1365-2710.1987.tb00531.x
Subject(s) - limulus amebocyte lysate , chromogenic , limulus , chromatography , medicine , chemistry , biology , immunology , paleontology , lipopolysaccharide
SUMMARY Parenterals, sterile preparations intended to be injected in man or animal, should be free from pyrogenic substances which are able to raise the thermostatic setting in the hypothalamus. This article gives an up‐to‐date review of the principal detection and quantification methods for these agents, with special attention on the chromogenic Limulus Amebocyte Lysate assay.