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STABILITY OF PROCAINE HYDROCHLORIDE IN A CARDIOPLEGIC SOLUTION CONTAINING BICARBONATE
Author(s) -
Synave R.,
Vergote A.,
Remon J. P.
Publication year - 1985
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/j.1365-2710.1985.tb00938.x
Subject(s) - procaine hydrochloride , procaine , bicarbonate , chemistry , carbon dioxide , chromatography , hydrochloride , anesthesia , organic chemistry , medicine
The influence of preparation methodology and storage conditions on pH and procaine stability, in a cardioplegic solution, was studied. A solution prepared with carbon dioxide in the head space and stored at ‐ 10°C showed acceptable stability.