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PLASMA XANTHINE LEVELS IN PREMATURE INFANTS TREATED FOR APNOEA WITH THEOPHYLLINE
Author(s) -
Hargreaves D. B.,
Lealman G. T.,
Mulley B. A.
Publication year - 1983
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/j.1365-2710.1983.tb01042.x
Subject(s) - theophylline , medicine , xanthine , anesthesia , pediatrics , chemistry , biochemistry , enzyme
SUMMARY Evidence is presented that oral theophylline doses of 3 mg per kg per 24 h in premature babies produces plasma levels of theophylline and caffeine of about 5 and 1–2 mg/l respectively in most subjects.