Premium
ABSORPTION OF ISOSORBIDE DINITRATE BY PVC INFUSION BAGS AND ADMINISTRATION SETS
Author(s) -
Lee M. G.,
FentonMay V.
Publication year - 1981
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/j.1365-2710.1981.tb00995.x
Subject(s) - isosorbide dinitrate , potency , absorption (acoustics) , isosorbide , chromatography , medicine , pharmacology , anesthesia , chemistry , materials science , organic chemistry , biochemistry , in vitro , composite material
SUMMARY Isosorbide dinitrate is shown to be absorbed onto PVC bags and administration sets, resulting in a fall in potency to about 70–80% of its initial value in the first 15–30 min of an i.v. infusion. The drug was not absorbed by glass or polypropylene.