Premium
Influence of culture conditions on growth and protective antigenicity of Clostridium chauvoei
Author(s) -
Cortiñas Teresa Inés,
Micalizzi Blas,
Guzman Ana María S.
Publication year - 1994
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1994.tb03438.x
Subject(s) - immunogenicity , antigenicity , microbiology and biotechnology , clostridium , chemistry , biology , immune system , immunology , antigen , bacteria , genetics
. The effect of culture conditions on growth and immunogenicity of Clostridium chauvoei were examined. The pH control and partial feeding of the carbon source at high concentrations were beneficial for growth. The biomass yield was significatively improved, however the butanol concentration reached toxic levels hampering further growth. For each experimental condition the immunogenicity of cells was tested. No differences were found with cells obtained at different temperatures, but it decreased significatively with the partial supply of the carbon source and pH control.