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The effect of veratrole on carotenoid biosynthesis by Phycomyces blakesleeanus
Author(s) -
Shlomai P.,
BenAmotz A.,
Margalith P.
Publication year - 1991
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1991.tb04443.x
Subject(s) - phycomyces blakesleeanus , phycomyces , carotenoid , biosynthesis , diphenylamine , biology , carotene , biochemistry , chemistry , stereochemistry , botany , organic chemistry , gene , mutant
A number of chemical compounds are known to affect the biosynthetic pathways of β‐carotene. Both site‐specific inhibitors as well as general stimulators of carotenogenesis have been described. It has been reported that veratrole enhances β‐carotene synthesis when applied to agar cultures of Phycomyces blakesleeanus but we found no significant stimulation of β‐carotene production in submerged culture. Moreover, veratrole in high concentrations (> 0.1% w/v), unlike diphenylamine, inhibits the formation of phytoene, resulting in an almost total block of carotenoid biosynthesis.