Premium
Catabolite repression vs derepression, an approach to differentiation during sporulation in Bacillus subtilis
Author(s) -
Bhaduri Saswata,
Bose Sushil K.
Publication year - 1991
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1991.tb02971.x
Subject(s) - derepression , bacillus subtilis , catabolite repression , psychological repression , glutamine , spore , strain (injury) , fed batch culture , biochemistry , dipicolinic acid , chemistry , enzyme repression , nucleotide , mutant , biology , microbiology and biotechnology , bacteria , amino acid , genetics , anatomy , gene expression , gene , fermentation
Glutamine, like glucose, repressed sporulation and the synthesis of mycobacillin and dipicolinic acid by Bacillus subtilis , and these syntheses were derepressed by dibutyryl cyclic GMP but not by dibutyryl cyclic AMP. Neither of these dibutyryl cyclic nucleotides affected sporulation or a number of spore‐associated parameters in the strain under normal physiological conditions. Mutants insensitive to glutamine repression were indifferent to the addition of either of the dibutyryl cyclic nucleotides both in the presence and in the absence of glutamine. Sporulation resulted from the remission of repression obtained under the catabolically active state.