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Reversal of the surface effects of chlorhexidine diacetate on cells of Providencia stuartii
Author(s) -
Ismaeel N.,
Furr J. R.,
Russell A. D.
Publication year - 1986
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1986.tb04299.x
Subject(s) - escherichia coli , biguanide , microbiology and biotechnology , pseudomonas aeruginosa , antidote , chlorhexidine , chemistry , providencia , biofilm , bacteria , enterobacteriaceae , biology , biochemistry , medicine , toxicity , organic chemistry , genetics , metformin , dentistry , gene , diabetes mellitus , endocrinology
Chlorhexidine diacetate (CHA) increased the hydrophobicity of the cell surface of cells of three strains of Providencia stuartii. Removal of at least some of the CHA from the cells by washing them with an appropriate antidote partially reversed the hydrophobicity‐increasing action of the biguanide. The effects of other treatments on cell surface hydrophobicity were examined with these strains and, for comparison, with two strains each of Escherichia coli and Pseudomonas aeruginosa: ethyl‐enediamine tetraacetic acid affected all strains, although not to the same extent, whereas thermal injury (55°C) produced marked changes only with the two E. coli strains.