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The Detection and Differentiation of Fibrinolytic Enzymes in Bacteria
Author(s) -
JEFFRIES L.,
BUCKLEY D. E.
Publication year - 1980
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1980.tb04723.x
Subject(s) - micrococcus luteus , streptomyces griseus , microbiology and biotechnology , bacteria , achromobacter , enzyme , pseudomonas , biology , trypsin , biochemistry , corynebacterium , bacteroides , fusobacterium , streptomyces , chemistry , staphylococcus aureus , genetics
Fibrinolytic enzymes produced by various bacteria were distinguished from activators of plasminogen and were further divided into trypsin‐like, thiol and metallo groups. Trypsin‐like enzymes of the serine subgroup were identified by the hydrolysis of a chromogenic tripeptide substrate highly specific for plasmin and were shown to occur in a wider range of bacteria than had previously been recorded. In addition to confirming the production of enzymes of this specificity by Pseudomonas maltophilia, Achromobacter lyticus and Streptomyces griseus , similar enzymes were found in five further species of Streptomyces , in certain strains of Corynebacterium pyogenes, Micrococcus luteus and Propionibacterium acnes and also in certain species of Bacteroides and Fusobacterium.