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Copper and Iron as Determinant Factors of Antibiotic Production by Pseudomonas reptilivora
Author(s) -
MARTINEZMOLINA E.,
RIO L. A. DEL,
OLIVARES J.
Publication year - 1976
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1976.tb00606.x
Subject(s) - copper , antibiotics , nitrogen , pseudomonas , chemistry , food science , bacteria , nuclear chemistry , biochemistry , biology , organic chemistry , genetics
Production by Pseudomonas reptilivora of three antibiotics, named A, B 1 and B 2 , took place in media containing either an inorganic or organic nitrogen source but only in the presence of available copper and iron. Higher yields were obtained in media containing inorganic nitrogen. Antibiotic synthesis was mediated by definite levels of copper and iron which determined the production of (a) the iron and copper‐dependent activity A, (b) the two copper‐dependent activities B 1 and B 2 , or (c) a mixture of the three.