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Studies on the Mechanism of the Antimicrobial Action of Oleuropein *
Author(s) -
Juven B.,
Henis Y.,
Jacoby B.
Publication year - 1972
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1972.tb03737.x
Subject(s) - oleuropein , antimicrobial , chemistry , lactobacillus plantarum , food science , biochemistry , bacteria , lactic acid , biology , antioxidant , organic chemistry , genetics
S ummary : Oleuropein, the bitter principle of green olives, is surface active; this and its effect on cell membranes, as demonstrated with human erythrocytes, seems to be the basis of its antimicrobial activity. Oleuropein effected a significant leakage of glutamate, potassium and inorganic phosphate from Lactobacillus plantarum. Oleuropein had no effect on the rate of glycolysis when added to resting cells of L. plantarum but it caused a decrease in the ATP content of the cells.