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Activity of Metronidazole against Experimental Tetanus and Gas Gangrene
Author(s) -
Freeman W. A.,
McFadzean J. A.,
Whelan J. P. F.
Publication year - 1968
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1968.tb00393.x
Subject(s) - metronidazole , gas gangrene , clostridium tetani , tetanus , chemoprophylaxis , microbiology and biotechnology , medicine , biology , vaccination , antibiotics , surgery , immunology
SUMMARY Metronidazole, a compound widely used in man with minimal side effects, has been shown to be highly active against experimental infections of Clostridium tetani and Cl. welchii in mice. It is too early to forecast what role the compound might have in the chemoprophylaxis of these infections in man.