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Biocidal Activities of Glutaraldehyde and Related Compounds
Author(s) -
Rubbo S. D.,
Gardner Joan F.,
Webb R. L.
Publication year - 1967
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1967.tb00277.x
Subject(s) - glutaraldehyde , bacillus anthracis , clostridium tetani , chemistry , spore , aqueous solution , microbiology and biotechnology , aldehyde , bacteria , biology , organic chemistry , tetanus , virology , genetics , vaccination , catalysis
S ummary . Glutaraldehyde in 2% aqueous alkaline solution is rapidly bactericidal and sporicidal, killing 99.99% of the spores of Bacillus anthracis and Clostridium tetani in 15 and 30 min, respectively. It exhibits some degree of tuberculocidal activity, but it appears to be inferior to several other disinfectants when challenged with a large inoculum. Fungicidal action has been demonstrated but not assessed quantitatively. Evidence is presented to show that biocidal activity depends on the availability of two free aldehyde groups in the molecule.