Premium
The Action of Ethylenediaminetetra‐acetic Acid on Pseudomonas aeruginosa
Author(s) -
Gray G. W.,
Wilkinson S. G.
Publication year - 1965
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1965.tb02138.x
Subject(s) - pseudomonas aeruginosa , alcaligenes faecalis , microbiology and biotechnology , chemistry , acetic acid , bacteria , biochemistry , biology , genetics
It has been shown that ethylenediaminetetra‐acetic acid (EDTA) has a direct bactericidal action against strains of Pseudomonas aeruginosa and Alcaligenes faecalis . The action against Ps. aeruginosa is considered to take the form of competition for a metal essential to the integrity of the cells: some of the factors influencing this antibacterial action have been discussed. From a study of the release of solutes from cells of Ps. aeruginosa , it was concluded that the action of EDTA takes place at the cell wall of the organism: an effect by EDTA on the isolated walls of sensitive organisms has been demonstrated.