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Antibiotic Production by Actinomycete Species on Nitrogen‐Deficient Media
Author(s) -
Considine R. G.,
Casida L. E.
Publication year - 1964
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1964.tb04908.x
Subject(s) - antibiotics , nitrogen , azotobacter , yeast extract , chemistry , ammonium , molybdenum , food science , fermentation , biochemistry , biology , bacteria , inorganic chemistry , organic chemistry , genetics
Summary: Actinomycetes isolated from nitrogen deficient Azotobacter plating medium were checked for antibiotic production on nitrogen deficient media and on these media with yeast extract or ammonium sulphate as nitrogen sources. In nitrogen deficient liquid media cobalt, molybdenum and citrate were required for growth and antibiotic formation. Evidence is presented that the antibiotics resulting from growth under these conditions are different from those produced when combined nitrogen is included in the medium, and it is suggested that this is an area for exploration for new antibiotics.