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Studies on the Dose Requirement for the Radiation Sterilization of Medical Equipment. II. A Comparison between Continuous and Fractionated Doses
Author(s) -
Burt Margaret M.,
Ley F. J.
Publication year - 1963
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1963.tb04799.x
Subject(s) - sterilization (economics) , bacillus pumilus , gamma irradiation , radiation , irradiation , radiation dose , radiochemistry , nuclear medicine , environmental science , materials science , toxicology , chemistry , medicine , physics , biology , optics , nuclear physics , philosophy , linguistics , currency , bacteria , foreign exchange market , genetics
S ummary : The lethal effect of gamma radiation on spores of Bacillus pumilus air dried on to a glass surface was measured by constructing dose‐survivor curves. In one set of experiments the doses used were delivered without interruption, and in another set they were fractionated in various ways with storage intervals between fractions of up to one week. The data presented confirms the view that the efficiency of sterilization by irradiation would not be affected by interruption of dose delivery as might occur in plant operation. A situation where effects might be observed is discussed.