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Premium Tooth bioengineering leads the next generation of dentistry
Author(s)
WANG YING,
PRESTON BRIAN,
GUAN GUOQIANG
Publication year2012
Publication title
international journal of paediatric dentistry
Resource typeJournals
PublisherBlackwell Publishing Ltd
International Journal of Paediatric Dentistry 2012; 22: 406–418 Background.  As a result of numerous rapid and exciting developments in tissue engineering technology, scientists are able to regenerate a fully functional tooth in animal models, from a bioengineered tooth germ. Advances in technology, together with our understanding of the mechanisms of tooth development and studies dealing with dentally derived stem cells, have led to significant progress in the field of tooth regeneration. Aim and design.  This review focuses on some of the recent advances in tooth bioengineering technology, the signalling pathways in tooth development, and in dental stem cell biology. These factors are highlighted in respect of our current knowledge of tooth regeneration. Results and conclusion.  An understanding of these new approaches in tooth regeneration should help to prepare clinicians to use this new and somewhat revolutionary therapy while also enabling them to partake in future clinical trials. Tooth bioengineering promises to be at the forefront of the next generation of dental treatments.
Subject(s)biology , dentistry , enamel paint , engineering , engineering ethics , human tooth , medicine , microbiology and biotechnology , oral health , permanent teeth , permanent tooth , regeneration (biology) , tooth loss
Language(s)English
SCImago Journal Rank1.183
H-Index62
eISSN1365-263X
pISSN0960-7439
DOI10.1111/j.1365-263x.2011.01206.x

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