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Oral mucous membrane pemphigoid in a 6‐year‐old boy: diagnosis, treatment and 4 years follow‐up
Author(s) -
MOSTAFA MOSTAFA I.,
HASSIB NEHAL F.,
NEMAT AMANY H.
Publication year - 2010
Publication title -
international journal of paediatric dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.183
H-Index - 62
eISSN - 1365-263X
pISSN - 0960-7439
DOI - 10.1111/j.1365-263x.2009.01002.x
Subject(s) - medicine , dermatology , differential diagnosis , gingivitis , pemphigoid , cicatricial pemphigoid , bullous pemphigoid , pathology , dentistry , immunology , antibody
Background. Childhood oral pemphigoid is extremely rare and usually takes the form of desquamative gingivitis. Case report. We describe a 6‐year‐old boy who presented with gingival bleeding, pain, eating difficulty, and peeling of the gums. Clinical examination revealed desquamative gingivitis with no extra‐oral involvement. The diagnosis was established as oral pemphigoid based on the clinical, histological, and immunofluorescence findings. Symptoms resolved on treatment with occlusive topical corticosteroids. The patient was a carrier of the HLA‐DQB 1 *0301 allele. Conclusion. Mucous membrane pemphigoid should be considered in the differential diagnosis of chronic desquamative gingivitis in childhood. Occlusive therapy with topical fluocinonide may alleviate the symptoms.