Premium
Intragastric Oil‐in‐Water Emulsion Fat Fraction Measured Using Inversion Recovery Echo‐Planar Magnetic Resonance Imaging
Author(s) -
Marciani L.,
Wickham M.,
Hills B.P.,
Wright J.,
Bush D.,
Faulks R.,
FILLERYTRAVIS A.,
Spiller R.C.,
Gowl P. A.
Publication year - 2004
Publication title -
journal of food science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 150
eISSN - 1750-3841
pISSN - 0022-1147
DOI - 10.1111/j.1365-2621.2004.tb11000.x
Subject(s) - in vivo , emulsion , magnetic resonance imaging , chemistry , nuclear magnetic resonance , chromatography , materials science , medicine , biology , biochemistry , radiology , physics , microbiology and biotechnology
The fat fraction of an oil‐in‐water emulsion was measured in vitro and in vivo in the gastric lumen using inversion recovery echo‐planar magnetic resonance imaging and a non‐exchanging, 2‐compartment longitudinal relaxation model. This predicted the oil emulsion fat fraction in vitro well (Pearson's R = 0.97). Intragastric measurements in vivo correlated well with nasogastric aspirates taken from the stomachs of 7 healthy human subjects ( R = 0.72). This method has potentially important applications in studying the properties of oil‐in‐water emulsions and also in assessing the intragastric distribution of fat emulsions in vivo and in correlating physiologic gastric emptying of fat and lipid blood absorption profiles.