Premium
Optimization of Lactic Acid Production by Lactobacillus delbrueckii through Response Surface Methodology
Author(s) -
TéllezLuis S.J.,
Moldes A.B.,
Alonso J.L.,
Vázquez M.
Publication year - 2003
Publication title -
journal of food science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 150
eISSN - 1750-3841
pISSN - 0022-1147
DOI - 10.1111/j.1365-2621.2003.tb09666.x
Subject(s) - lactic acid , corn steep liquor , fermentation , response surface methodology , food science , lactobacillus , yeast extract , yeast , chemistry , productivity , lactobacillaceae , bacteria , biochemistry , biology , chromatography , genetics , macroeconomics , economics
This article describes the optimization through response surface methodology of a low‐cost medium based on Corn Steep Liquor (CSL) for lactic acid production by Lactobacillu delbrueckii NRRL B445. The effect of the fermentation time was also considered. A maximum lactic acid concentration (93.4 g/L) was predicted using 15 g of CSL/L and 6 g of yeast extract/L at a fermentation time of 80.1 h. However, the maximum productivity (3.50 g/L/h) was predicted by using 15 g of CSL/L, 6 g of yeast extract/L, and 8.9 g of peptone/L after 24 h. From an economical perspective, better results were obtained using 15 g of CSL/L, 6 g of yeast extract/L, and 8.9 g of peptone/L after 24 h. From an economical perspective, better results were obtained using 15 g of CSL/L alone and 24 h, achieving a maximum economical productivity of 229.7 g of lactic acid per hour and considerable savings in nutrients.