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Oxytetracycline Residues in Cultured White Shrimp Tissue by HPLC and a Microbial Receptor Assay
Author(s) -
BermúdezAlmada M.C.,
PérezTello M.G.,
ValenzuelaQuintanar A.I.,
VázquezMoreno L.
Publication year - 1999
Publication title -
journal of food science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 150
eISSN - 1750-3841
pISSN - 0022-1147
DOI - 10.1111/j.1365-2621.1999.tb15100.x
Subject(s) - oxytetracycline , penaeus , shrimp , high performance liquid chromatography , chromatography , residue (chemistry) , chemistry , receptor , biology , food science , biochemistry , antibiotics , fishery
The residue depletion of oxytetracycline (OTC) from muscle tissue of cultured shrimp ( Penaeus vannamei ) was evaluated. OTC was measured using high performance liquid chromatography (HPLC) and a microbial receptor assay. Samples were taken on days 7, 14 and 21 during the treatment and 23, 25 and 28 after the treatment. OTC was detectable in all groups after 7 days depletion time at concentrations of 0.28, 0.19 and 0.05 μg/g for diets containing 500, 250 and 100 mg/kg OTC, respectively. Results by the microbial receptor assay were in good agreement with those by HPLC.