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Examination of Chili Pepper and Nutmeg Oleoresins Using the Salmonella/Mammalian Microsome Mutagenicity Assay
Author(s) -
BUCHANAN R. L.,
GOLDSTEIN S.,
BUDROE J.D.
Publication year - 1982
Publication title -
journal of food science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 150
eISSN - 1750-3841
pISSN - 0022-1147
DOI - 10.1111/j.1365-2621.1982.tb11094.x
Subject(s) - nutmeg , oleoresin , pepper , chili pepper , salmonella , microsome , chemistry , gingerol , capsaicin , ames test , myristica fragrans , food science , toxicology , biology , in vitro , botany , biochemistry , bacteria , receptor , genetics
Past investigations have suggested that various arylalkene spice compounds warrant further study as possible naturally occurring mutagens and/or carcinogens. The present study carried out a detailed examination of nutmeg oleoresin, myristicin, chili pepper oleoresin, capsaicin, and vanillylamine for in vitro mutagenicity using the Salmonella /mammalian microsome mutagenicity assay. None of the materials tested displayed significant mutagenicity over a wide range of concentrations.