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IN VITRO STUDIES ON SAPONIN—VITAMIN COMPLEXATION
Author(s) -
WEST L. G.,
GREGER J. L.
Publication year - 1978
Publication title -
journal of food science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 150
eISSN - 1750-3841
pISSN - 0022-1147
DOI - 10.1111/j.1365-2621.1978.tb15308.x
Subject(s) - saponin , chemistry , in vitro , vitamin , glycyrrhizin , cholesterol , digitonin , food science , biochemistry , biology , pharmacology , medicine , alternative medicine , pathology , enzyme
The possibility that certain saponins produce growth depression by complexing fat soluble vitamins with a mechanism similar to saponin‐cholesterol complexation was studied. An in vitro procedure was developed to quantitate the formation of addition complexes in aqueous solutions. Saponins studied included digitonin, ammoniated glycyrrhizin, quillaja bark saponin, and saponin‐containing extracts from alfalfa leaves and roots and soybeans. Vitamins tested included provitamin D 3 and vitamins E, A and D 3 . The study demonstrated that the saponins did not complex fat soluble vitamins in a manner similar to the complexation of cholesterol.