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NITROSAMINES AND THE INHIBITION OF Clostridia IN MEDIUM HEATED WITH SODIUM NITRITE
Author(s) -
WASSERMAN AARON E.,
HUHTANEN CHARLES N.
Publication year - 1972
Publication title -
journal of food science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 150
eISSN - 1750-3841
pISSN - 0022-1147
DOI - 10.1111/j.1365-2621.1972.tb02751.x
Subject(s) - clostridia , chemistry , sterilization (economics) , sodium nitrite , chromatography , nitrite , food science , nitroso compounds , clostridium , bacteria , organic chemistry , biology , genetics , monetary economics , economics , foreign exchange market , foreign exchange , nitrate
During sterilization of a culture medium in the presence of NaNO 2 an inhibitor for the growth of Clostridium was observed. The possibility this might be certain volatile N‐nitroso compounds was investigated using CC‐MS. The minimum inhibitory concentration (MIC) of NO 2 ‐ in the medium autoclaved with NO; was 40 ppm; in medium to which NO; was added aseptically, the MIC was 640 ppm. Chromatograms showed peaks with retention times similar to N‐nitroso compounds; however, structure confirmation with MS showed none contained a nitrosoamine and additional experiments confirmed nitrosamines had no inhibitory effects to growth of Clostridiu.