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Effect of tricalcium aluminate on the properties of tricalcium silicate–tricalcium aluminate mixtures: setting time, mechanical strength and biocompatibility
Author(s) -
Liu W.N.,
Chang J.,
Zhu Y.Q.,
Zhang M.
Publication year - 2011
Publication title -
international endodontic journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.988
H-Index - 119
eISSN - 1365-2591
pISSN - 0143-2885
DOI - 10.1111/j.1365-2591.2010.01793.x
Subject(s) - biocompatibility , compressive strength , materials science , aluminate , mineral trioxide aggregate , calcium silicate , composite material , cement , chemical engineering , dentistry , metallurgy , medicine , engineering
Liu W‐N, Chang J, Zhu Y‐Q, Zhang M. Effect of tricalcium aluminate on the properties of tricalcium silicate‐tricalcium aluminate mixtures: setting time, mechanical strength and biocompatibility. International Endodontic Journal , 44 , 41–50, 2011. Abstract Aim To prepare biphasic mixtures by adding Ca 3 Al 2 O 6 into Ca 3 SiO 5 and to evaluate the effect of Ca 3 Al 2 O 6 on physical and ex vivo biological properties of the Ca 3 SiO 5 /Ca 3 Al 2 O 6 mixtures derived from mineral trioxide aggregate (MTA). Methodology Combinations of Ca 3 SiO 5 and Ca 3 Al 2 O 6 (0, 5%, 10% and 15%) powders were mixed with deionized water. After hydration, setting time, compressive strength, ex vivo bioactivity and biocompatibility of each mixture were investigated and compared to pure Ca 3 SiO 5 . Results With the addition of Ca 3 Al 2 O 6 from 0% to 15%, the initial setting time and final setting time of the Ca 3 SiO 5 /Ca 3 Al 2 O 6 mixtures decreased from 110 to 43 min and from 220 to 97 min, respectively ( P ≤ 0.05). However, the compressive strength increased from 6.75 to 16.20 MPa after one day ( P ≤ 0.05) and from 17.73 to 29.13 Mpa after 28 days. Furthermore, the mixtures with 10% Ca 3 Al 2 O 6 or less had similar bioactivity and biocompatibility when compared to the pure Ca 3 SiO 5 . Conclusions The addition of Ca 3 Al 2 O 6 into Ca 3 SiO 5 accelerated the hydration process, reduced the setting time and improved the compressive strength. Furthermore, these mixtures were bioactive and biocompatible and had a stimulatory effect on the L929 cell growth when the content of Ca 3 Al 2 O 6 was below 10%. Therefore, the mixtures with 10% Ca 3 Al 2 O 6 produced the best compromise between hydration and ex vivo biological properties.