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Associations of endodontic symptoms and signs with particular combinations of specific bacteria
Author(s) -
GOMES B. P. F. A.,
LILLEY J. D.,
DRUCKER D. B.
Publication year - 1996
Publication title -
international endodontic journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.988
H-Index - 119
eISSN - 1365-2591
pISSN - 0143-2885
DOI - 10.1111/j.1365-2591.1996.tb01164.x
Subject(s) - peptostreptococcus , prevotella , eubacterium , fusobacterium nucleatum , microbiology and biotechnology , prevotella intermedia , fusobacterium , biology , obligate anaerobe , anaerobic bacteria , bacteria , anaerobic exercise , bacteroides , physiology , porphyromonas gingivalis , genetics
Summary Significant associations have been reported between (a) specific bacterial species isolated from root canals and (b) between individual bacterial species and endodontic symptoms and signs. The prime objective of this study was to determine whether particular combinations of specific bacteria are associated with individual endodontic symptoms and signs. Seventy root canals were investigated microbiologically taking care to maintain the viability of obligate anaerobes, which accounted for 64% of the total species isolated, including Peptostreptococcus micros, Prevotella melaninogenica, Prevotella oralis, Eubacterium aerofaciens, Eubacterium lentum, Fusobacterium nucleatum, Prevotella buccae and Prevotella intermedia. Significant associations were found between individual clinical features and the following pairs of species: (a) pain (37 cases) and Peptostreptococcus spp./Prevotella spp., Peptostreptococcus spp./Prevotella melaninogenica, Pstr. micros/Prev. melaninogenica (all P < 0.01); (b) swelling (23 cases) and Pstr. micros/Prevotella spp. ( P < 0.01); (c)‘Wet’canal (57 cases) and Prevotella spp./Eubacterium spp. ( P < 0.01), Peptostreptococcus spp./Eubacterium spp. ( P < 0.05). Thus data from this investigation suggests that statistically significant associations exist between individual endodontic symptoms and signs and particular combinations of specific bacteria.